- esthemax has exceeded the standard liquid Microneedling systems with the new Liquid needle pdrn ampoules. These contain over 135000 spicules per 5ml ampoule. These spicules create micro punctures allowing the skin to absorb PDRN - the revolutionary salmon DNA. This works by stimulating the skins natural  healing process and triggering the production of collagen and elastin. This results in visibly brighter, plumper, firmer, younger looking skin.